Cyclopropyl 2-fluorobenzyl ketone
Cyclopropyl 2-fluorobenzyl ketone
Cyclopropyl 2-fluorobenzyl ketone ikoreshwa nkigihe cya Prasugrel.
Prasugrel ni antiplatelet ya thiophenopyridine yakozwe na Eli Lilly na daiichisankyo, uruganda rukora imiti mu Buyapani.Nibiyobyabwenge byabanjirije.Ikora molekile ikora nyuma yo guhinduranya binyuze muri cytochrome P450 mu mwijima kandi igahuza na reseptor ya P2Y12 kugirango ikore igikorwa cyo kurwanya platine.Ubuvuzi bwa Clinical bwerekanye ko 60 mg ikinini gifite anticoagulant nziza kuruta mg 300 zisanzwe hamwe na 600 mg yiyongereye ya clopidogrel, ishobora kugabanya ibyago byose byindwara z'umutima, ubwonko n'urupfu bitewe n'indwara z'umutima ku kigero cya 20%, kandi bigira ingaruka byihuse , ingaruka nziza zo kuvura, kurwanya ibiyobyabwenge neza na bioavailable, hamwe nuburozi buke.
JIN DUN Ubuvuzi bufiteImpamyabumenyi ya ISO kandi yujuje ubuziranenge bwa GMP, yakoresheje inzobere mu kuvura ibiyobyabwenge mu gihugu no mu mahanga bifite uburambe bukomeye bwo kuyobora R&D ya sosiyete.
TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
Ubuvuzi bwa Jindun bufite itsinda ryabakozi ba R&D babigize umwuga, kandi bukoresha impuguke nyinshi zo mu gihugu ndetse n’amahanga mu kuvura ibiyobyabwenge kugira ngo ziyobore R&D, bigatuma synthesis yacu neza kandi neza.
Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
1.Hindura abahuza bashya cyangwa APIs.Kimwe nkuko byavuzwe haruguru kugabana, abakiriya bafite ibyo bakeneye kuri Intermediates cyangwa APIs, kandi ntibashobora kubona ibicuruzwa bikenewe kumasoko, noneho turashobora gufasha Customize.
2.Gutunganya neza ibicuruzwa bishaje.Itsinda ryacu rizafasha mugutezimbere no kunoza umusaruro nkuwo inzira ya reaction ishaje, igiciro cyumusaruro ni kinini, kandi imikorere ni mike.Turashobora gutanga ibyangombwa byuzuye byo guhererekanya ikoranabuhanga no kunoza imikorere, gufasha abakiriya kubyara umusaruro mwiza.
Kuva ibiyobyabwenge byibasiye INDs, JIN DUN Medical iraguhaumurongo umwe wihariye R&D ibisubizo.
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