Hagati ya Moxonidine
Irashobora gushimisha hagati ya α2 yakira kandi igatera ingaruka zo kurwanya umuvuduko ukabije, bisa na clonidine.Igipimo cyo kwinjiza umunwa (90%) hamwe na bioavailable (88%) byombi biri hejuru, kandi nta ngaruka-yambere yatanzwe.Umubare munini wamaraso ugaragara nyuma yamasaha 1 kugeza kuri 3 nyuma yo gufata ibiyobyabwenge.Byinshi muri byo bisohoka nimpyiko.t1 / 2 ni amasaha agera kuri 2.Clinical ikoreshwa kuri hypertension.
Ibara ridafite ibara cyangwa umuhondo muto.Ahantu ho gushonga ni 23-25.5 ° C, aho gutekera ni 159 ° C, ubucucike bugereranije ni 1.113 (15/15 ° C), naho indangagaciro ni 1.5442.Byoroshye gushonga muri alcool na ether, hafi yo kudashonga mumazi.
Iki gicuruzwa gifite impumuro nziza ya fennel kandi gikoreshwa kenshi mugutegura jasimine, lilac nibindi biryoha, kandi birakwiriye mugutegura parufe.Iki gicuruzwa nikirungo kiribwa cyemewe na GB2760-86 yigihugu cyanjye.Ikoreshwa cyane mugutegura uburyohe nka vanilla, shokora, kakao, almonde, na pacha.Irakoreshwa kandi muri synthesis organique kandi nkigisubizo.
Kugabanuka kwa anisaldehyde.Cannizzaro ifata anise, formaldehyde na sodium hydroxide muri Ethanol kugirango itange inzoga ya p-mikorerexybenzyl.
Ethanol imaze kugarurwa no kuyungurura, igipimo cyamavuta cyabonetse kubisubizo gikuramo benzene, acide yongeramo aside acike, hanyuma ikabangikanya na sodium bicarbonate kuri alkaline nkeya.Nyuma yo gukaraba namazi kugirango utabogamye, benzene isubizwa no kuyungurura, kandi ibisigara bikorerwa vacuum kugirango ubone inzoga ya p-mikorerexy Benzyl.
Cyakora mukubyutsa presinaptic yo hagati α2-yakira.Ingaruka zayo zirwanya ubukana zirasa na calcium antagonist nifedipine na ACE inhibitor capopril.Byakoreshejwe kuri hypertension ya ngombwa.
Ibipimo ngenderwaho :urwego rwumushinga
Inyuma :Ibara ridafite ibara ryumuhondo ryoroshye
Amapaki :225kg / ingoma
Suzuma ibirimo ≥99.0%
JIN DUN Ubuvuzi bufiteImpamyabumenyi ya ISO kandi yujuje ubuziranenge bwa GMP, yakoresheje inzobere mu kuvura ibiyobyabwenge mu gihugu no mu mahanga bifite uburambe bukomeye bwo kuyobora R&D ya sosiyete.
TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
Ubuvuzi bwa Jindun bufite itsinda ryabakozi ba R&D babigize umwuga, kandi bukoresha impuguke nyinshi zo mu gihugu ndetse n’amahanga mu kuvura ibiyobyabwenge kugira ngo ziyobore R&D, bigatuma synthesis yacu neza kandi neza.
Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
1.Hindura abahuza bashya cyangwa APIs.Kimwe nkuko byavuzwe haruguru kugabana, abakiriya bafite ibyo bakeneye kuri Intermediates cyangwa APIs, kandi ntibashobora kubona ibicuruzwa bikenewe kumasoko, noneho turashobora gufasha Customize.
2.Gutunganya neza ibicuruzwa bishaje.Itsinda ryacu rizafasha mugutezimbere no kunoza umusaruro nkuwo inzira ya reaction ishaje, igiciro cyumusaruro ni kinini, kandi imikorere ni mike.Turashobora gutanga ibyangombwa byuzuye byo guhererekanya ikoranabuhanga no kunoza imikorere, gufasha abakiriya kubyara umusaruro mwiza.
Kuva ibiyobyabwenge byibasiye INDs, JIN DUN Medical iraguhaumurongo umwe wihariye R&D ibisubizo.
JIN DUN Ubuvuzi bushimangira gushinga itsinda rifite inzozi, gukora ibicuruzwa byiyubashye, byitondewe, bikomeye, kandi byose kugirango ube umufatanyabikorwa wizewe ninshuti yabakiriya!