4-chloro-n- (4,5-dihydro-1h-imidazol-2-yl) -6-mikorerexy-2-methyl-5-pyrimidinamin;
4-chloro-n- (4,5-dihydro-1h-imidazol-2-yl) -6-mikorerexy-2-methyl-5-pyrimidinamin;
Ikora mukubyutsa presinaptic ya alpha 2- yakira.Ingaruka ya hypotensive isa niyya nifedipine, calcium antagonist, na capopril, inhibitor ya ACE.Kuri hypertension ya ngombwa.
Iki gicuruzwa kigomba gukurikiza ihame ryimiti yihariye.Mubisanzwe tangira uhereye kumupanga muto, ni ukuvuga 0.2mg, rimwe kumunsi, ufashwe mugitondo.Guhindura ibipimo bigomba gukorwa mugihe cyibyumweru bitatu kugeza ibisubizo bishimishije bibonetse.Igipimo gisanzwe ni 0.2mg rimwe, kabiri kumunsi (mugitondo nimugoroba).Igipimo ntarengwa kuri buri gihe ntigishobora kurenga 0.4mg, kandi igipimo ntarengwa cya buri munsi ntigishobora kurenga 0,6mg.Ku barwayi bafite ikibazo cyo kubura impyiko zoroheje cyangwa ziciriritse, ikinini kimwe ntigishobora kurenga mg 0.2 cyangwa ikinini cya buri munsi ntigishobora kurenga mg 0.4.
Iki gicuruzwa ni α2-reseptor agonist, niwo muti wa imidazoline antihypertensive.Ikoreshwa kuri hypertension iringaniye kandi ikabije.
Kuberako ibuza gusohora no kugenda kwinzira zo munda, birakwiriye kandi kubarwayi ba hypertension barwaye ibisebe.Guhuza iyi miti na diuretique birashobora kunoza imikorere neza.Numuti ukomeye wo kurwanya antivypertensique nu muti wa kabiri urwanya antihypertensive.Ikoreshwa cyane cyane mubuvuzi bw'amaso.Iki gicuruzwa gifite ingaruka zo kugabanya umuvuduko wimbere, kandi ntabwo bigira ingaruka kuburyo bwo guhindura ijisho no guhanga amaso.Irashobora kugabanya imiyoboro y'amaraso mu jisho, kugabanya umusaruro wo gusetsa mu mazi, kandi ikagera ku ngaruka zo kugabanya umuvuduko w'amaraso.Itangira gukurikizwa nyuma yiminota 15 ijisho rimaze gutemba kandi irashobora gukomeza ingaruka mugihe cyamasaha 8.
Bisanzwe ：EP10
Suzuma ibirimo ：97.5-102.0%
Inyuma:Cyera cyangwa hafi mugihe ifu
Ipaki:1kg / igikapu cyangwa nkuko bisabwa nabakiriya
JIN DUN Ubuvuzi bufiteImpamyabumenyi ya ISO kandi yujuje ubuziranenge bwa GMP, yakoresheje inzobere mu kuvura ibiyobyabwenge mu gihugu no mu mahanga bifite uburambe bukomeye bwo kuyobora R&D ya sosiyete.
TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
Ubuvuzi bwa Jindun bufite itsinda ryabakozi ba R&D babigize umwuga, kandi bukoresha impuguke nyinshi zo mu gihugu ndetse n’amahanga mu kuvura ibiyobyabwenge kugira ngo ziyobore R&D, bigatuma synthesis yacu neza kandi neza.
Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
1.Hindura abahuza bashya cyangwa APIs.Kimwe nkuko byavuzwe haruguru kugabana, abakiriya bafite ibyo bakeneye kuri Intermediates cyangwa APIs, kandi ntibashobora kubona ibicuruzwa bikenewe kumasoko, noneho turashobora gufasha Customize.
2.Gutunganya neza ibicuruzwa bishaje.Itsinda ryacu rizafasha mugutezimbere no kunoza umusaruro nkuwo inzira ya reaction ishaje, igiciro cyumusaruro ni kinini, kandi imikorere ni mike.Turashobora gutanga ibyangombwa byuzuye byo guhererekanya ikoranabuhanga no kunoza imikorere, gufasha abakiriya kubyara umusaruro mwiza.
Kuva ibiyobyabwenge byibasiye INDs, JIN DUN Medical iraguhaumurongo umwe wihariye R&D ibisubizo.
JIN DUN Ubuvuzi bushimangira gushinga itsinda rifite inzozi, gukora ibicuruzwa byiyubashye, byitondewe, bikomeye, kandi byose kugirango ube umufatanyabikorwa wizewe ninshuti yabakiriya!
