3- (1- (Dimethylamino) ethyl] phenol ikoreshwa nkigihe cyo hagati ya tartrate ya Rivastigmine.
Rivastigmine tartrate ni rivastigmine imiti yindwara ya Alzheimer, rivastigmine ninkomoko ya physostigmine na Novartis kunshuro yambere yateje imbere izina ryubucuruzi Exelon (exelon), molekile ifite imiterere ya karbamate, ni ubwoko bwa aside amine ya seline cerebral cholinesterase inhibitor, irashobora kandi kubuza acetylcholinesterase na butyrylcholinesterase, neuron ya cholinergique itinda kurekura kwangirika kwa acetylcholine ningufu ziteza imbere imitsi ya cholinergique, birashobora kunoza imikorere yimikorere yubwenge yunganirwa na cholinergique, bityo bikazamura imikorere yubwenge bwabarwayi ba Alzheimer.Rivastigmine plasma protein ihuza ni ntege, byoroshye binyuze mumaraso yubwonko bwamaraso, ifite urwego rwo hejuru rwo guhitamo ubwonko.Ntabwo ikora gusa mubikorwa byubwonko bwubwonko bworoshye cyane na hippocampus, ariko kandi biranabuza guhagarika ubwoko bwiganje bwa AChE mubwonko, bikaviramo kugabanuka kwingaruka zingaruka za cholinergique.Rivastigmine muri vivo igice cyubuzima ni kigufi kandi igihe kirekire cyibikorwa.Bitandukanye na tacrine, iki gicuruzwa muri hippocampus na cortex ya G1 enzyme yo kubuza imbaraga irakomeye.Ivuriro ryo kuvura indwara yo mu bwoko bwa Alzheimer yoroheje cyangwa yoroheje, cyangwa indwara ya Alzheimer irashobora gukekwa ko ari indwara ya Alzheimer.
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TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
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Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
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