Rivaroxaban （S) -Rivaroxaban; BAY 59-7939; RivaroxabanIsomer; Rivaroxaban;
Rivaroxaban （S) -Rivaroxaban; BAY 59-7939; RivaroxabanIsomer; Rivaroxaban;
Ikoreshwa mubarwayi bakuze bafite uburyo bwo kubaga ikibuno cyangwa gusimbuza ivi kugirango birinde imiyoboro y'amaraso (VTE).
Ikoreshwa mukurinda cyangwa kugabanya imiterere ya trombose, imitsi yimbitse (DVT) hamwe na embolisme yimpyisi (PE) nyuma yo kubagwa ikibuno cyangwa ivi.
Igipimo gisabwa ni umunwa rivaroxaban 10mg, rimwe kumunsi.Rivaroxaban 10mg irashobora gufatwa nibiryo cyangwa wenyine.Rivaroxaban ibinini 15mg cyangwa 20mg bigomba gufatwa nibiryo.
bisanzwe: usp40
Suzuma: 99-102%
Inyuma: Ifu yera
Ipaki: 25kg / ingoma
Fata 4- (4-aminophenyl) morpholin-3-imwe (SM-1), (S) -N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) ni ibikoresho byo gutangira .Nyuma ya kondegene, cycleisation, aminolysis na acylation, rivaroxaban itaboneka iraboneka, kandi rivaroxaban yarangije gutunganywa.
Gutegura: Iki gicuruzwa nikibaho gitukura cya firime.
Ibikoresho:
Intandaro ya tablet: microcrystalline selulose, sodium ya croscarmellose, monohydrate ya lactose, hypromellose, sodium lauryl sulfate, magnesium stearate
Igipfukisho: polyethylene glycol, hypromellose, dioxyde ya titanium, okiside itukura
Rivaroxaban numuti watoranijwe cyane, umunwa uhagarika ibintu Xa.Binyuze mu guhitamo cyane no guhatanira kubuza ibintu kubuntu no guhuza ibikorwa Xa hamwe na prothrombine, ongera igice cya tromboplastine igice cyakorewe (PT) hamwe nigihe cya prothrombin (aPTT) muburyo bushingiye kumupanga, bishobora guhagarika isumo ya coagulation Inzira ya endogenous na exogenous kubuza umusaruro wa trombine na trombose.Rivaroxaban ntabwo ibuza trombine (ibintu bikora Ⅱ), nta nubwo yerekanye ko igira ingaruka kuri platine
Itandukaniro ryingenzi hagati ya rivaroxaban na fondaparinux / heparin nuko bidasaba uruhare rwa antithrombine III kandi irashobora kurwanya muburyo butaziguye Xa;mugihe heparin isaba antithrombine III gukora, kandi Nta ngaruka igira kubintu Xa murwego rwa prothrombine.
JIN DUN Ubuvuzi bufiteImpamyabumenyi ya ISO kandi yujuje ubuziranenge bwa GMP, yakoresheje inzobere mu kuvura ibiyobyabwenge mu gihugu no mu mahanga bifite uburambe bukomeye bwo kuyobora R&D ya sosiyete.
TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
Ubuvuzi bwa Jindun bufite itsinda ryabakozi ba R&D babigize umwuga, kandi bukoresha impuguke nyinshi zo mu gihugu ndetse n’amahanga mu kuvura ibiyobyabwenge kugira ngo ziyobore R&D, bigatuma synthesis yacu neza kandi neza.
Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
1.Hindura abahuza bashya cyangwa APIs.Kimwe nkuko byavuzwe haruguru kugabana, abakiriya bafite ibyo bakeneye kuri Intermediates cyangwa APIs, kandi ntibashobora kubona ibicuruzwa bikenewe kumasoko, noneho turashobora gufasha Customize.
2.Gutunganya neza ibicuruzwa bishaje.Itsinda ryacu rizafasha mugutezimbere no kunoza umusaruro nkuwo inzira ya reaction ishaje, igiciro cyumusaruro ni kinini, kandi imikorere ni mike.Turashobora gutanga ibyangombwa byuzuye byo guhererekanya ikoranabuhanga no kunoza imikorere, gufasha abakiriya kubyara umusaruro mwiza.
Kuva ibiyobyabwenge byibasiye INDs, JIN DUN Medical iraguhaumurongo umwe wihariye R&D ibisubizo.
JIN DUN Ubuvuzi bushimangira gushinga itsinda rifite inzozi, gukora ibicuruzwa byiyubashye, byitondewe, bikomeye, kandi byose kugirango ube umufatanyabikorwa wizewe ninshuti yabakiriya!
![Casp ungin Acetate; Caspofungin acetate; Cancidas; Acetate ya Caspofungin [USAN: BAN: JAN];](http://cdn.globalso.com/jindunchem-med/fbe17385-300x300.jpg)