Shanghai yatangije imiti gakondo y’abashinwa n’imyiteguro yoroshye hamwe nubuvuzi butari imiti kugirango ifashe abantu kurwanya ibicurane

1.Shanghai yatangije imiti gakondo yubushinwa hamwe nimyiteguro yoroshye hamwe nubuvuzi butari imiti kugirango ifashe abantu kurwanya ibicurane.

Ubuyobozi bw’Umujyi wa Shanghai bw’Ubuvuzi gakondo bw’Abashinwa bwatangaje ku ya 5 ko ikigo cy’igihugu gishinzwe gukumira no kurwanya indwara z’ibyorezo by’ubuvuzi bw’Abashinwa (Shanghai) cyafashe iya mbere mu gutegura gahunda yo gukumira no kurwanya imiti y’Abashinwa yo mu 2023 ibicurane by’ibiza muri Shanghai (Ikigeragezo) . .

Mu gihe c'itumba n'itumba, ikirere kirashyuha n'ubukonje, itandukaniro ry'ubushuhe hagati y'ijoro n'ijoro rirahinduka, kandi indwara zanduza ibihe zinjiye mu gihe kinini kandi c'ibyorezo.Vuba aha, umubare w'abarwayi bafite ibicurane A n'izindi ndwara wakiriwe n'ibitaro bikuru byo muri Shanghai byiyongereye.Iyi gahunda igamije guha agaciro gakomeye ibiranga ibyiza n’ubuvuzi gakondo bw’Abashinwa mu gukumira no kuvura ibicurane.

Zhang Wei, umwe mu banditsi b'iyi gahunda, umuyobozi wungirije w'itsinda ry'impuguke za COVID-19 rishinzwe kuvura imiti gakondo y'Abashinwa akaba n'umuyobozi w'ishami rishinzwe indwara y'ibihaha y'ibitaro bya Shuguang, yemeza ko iterambere ry'ibicurane (ibicurane) ahanini ryigenga kugarukira.Bamwe mu bana bafite intege nke ndetse n’abasaza bafite uburwayi bw’ibanze barashobora gutera izindi ngorane ziterwa n’indwara zidasanzwe, ari nazo zibandwaho mu gukumira no kuvura imiti gakondo y’Abashinwa n’ubuvuzi bw’iburengerazuba.Yatangarije abanyamakuru ko ubuvuzi gakondo bw’Abashinwa bwizera ko ibicurane biri mu cyiciro gikonje.Dukurikije imyumvire gakondo, gusuzuma no kuvura ahanini bishingiye kuri sisitemu yo gutandukanya syndrome nuburyo bwo kuvura bwa meridiya esheshatu, gutandukanya syndrome ya Weiqi na Yingxue, hamwe na sisitemu yo gutandukanya syndrome hamwe nuburyo bwo kuvura jiao eshatu, no kwitabwaho ihembwa mugukoresha hamwe gushimangira no gukuraho ibintu bitera indwara mubyiciro.

Ati: “Ibicurane ahanini bigarukira kandi birashobora gukira mu gihe gito nyuma yo kuvurwa ibimenyetso rusange no gutabara TCM.”Zhang Wei yagaragaje ko, usibye imiti gakondo y’abashinwa ndetse n’imyiteguro yoroshye isabwa muri iyi gahunda, ibitaro bikomeye bya TCM muri Shanghai bifite uburambe bukomeye mu gusuzuma no kuvura ibicurane, ndetse n’imyiteguro y’ibitaro ndetse n’ibisabwa.

Biravugwa ko kwanduza vuba aha ari H1N1.Ugereranije n'imbeho isanzwe, irandura cyane, ifite umuriro mwinshi kandi ikamara igihe kirekire, ifite ibimenyetso bigaragara, kandi ifite indwara ndende.

Xue Zheng, umwanditsi wa gahunda y’abana akaba n’umuyobozi w’ishami ry’ubuvuzi bw’abana bo mu bitaro by’umujyi wa Shanghai by’ubuvuzi gakondo bw’Abashinwa, yemeza ko abana bafite munsi y’imyaka 5 bashobora kwandura ibicurane.Abana barashobora kwandura ibicurane kandi bafite ibimenyetso bikomeye kubera ibihaha byabo byoroshye.Ubuvuzi gakondo bw'Abashinwa bugira uruhare runini mu gukumira no kuvura ibicurane ku bana, cyane cyane mu kuvura ibicurane A, bishobora kubuza ikwirakwizwa n'ubwiyongere bwa virusi, bigatera vuba ibimenyetso, kandi bifite umurongo mugari.Indwara z'abana mu bitaro bikuru by'Ubushinwa n'Uburengerazuba nazo zifite imyiteguro y'ibitaro ikuze ikoreshwa cyane mu mavuriro.

Uyu mugambi washyizeho amasezerano y’ubuvuzi gakondo bw’Abashinwa hamwe n’imiti gakondo y’Abashinwa ndetse n’imyiteguro yoroshye yo kuvura ibicurane by’abana, inasaba kandi uburyo bw’ubuvuzi bworoshye kandi buhendutse bw’ubuvuzi gakondo bw’Ubushinwa.Ababyeyi barashobora gukora ubuvuzi gakondo bwabashinwa binyuze muburyo bwo kuvura hanze nko kuvura indyo yuzuye, massage, ingingo zamatwi, kubishyira hamwe no kuvura imibavu kugirango bafashe abana kunoza ibimenyetso byihuse no gukira ubuzima vuba bishoboka.

2.Abashakashatsi ba siyansi bavumbuye urukurikirane rwibintu birwanya hepatoma biva mu gihingwa cy’imiti Artemisia annua.

Ishuri rya Kunming Institute of Botany, Ishuri Rikuru ry’Ubumenyi ry’Ubushinwa, ryatangaje ku ya 21 ko itsinda ry’ubushakashatsi bwa Chen Jijun ryabonye urukurikirane rw’ibiti bya sesquiterpene bifite ibikorwa byo kurwanya kanseri y’umwijima biva mu gihingwa cy’imiti Artemisia scoparia.Ibisubizo bijyanye nubushakashatsi biherutse gusohoka mu kinyamakuru kizwi cyane ku rwego mpuzamahanga cyitwa Signal Transmission na Targeted Therapy.

Kanseri y'umwijima ni ikibyimba kibi kibangamira ubuzima bw'abantu.Buri mwaka, umubare w'abanduye kanseri y'umwijima ku isi urenga 840000, naho impfu ziterwa na kanseri y'umwijima zigera ku 780000, mu gihe abagera kuri 50% banduye mu Bushinwa.Kugeza ubu, hari enye za tyrosine kinase inhibitor, sorafenib, regafinil, lovatinib na cabotinib, imwe mu mitsi yo mu bwoko bwa endothelial growth factor reseptor 2 antagonist, ramolumab, hamwe na PD-1 inhibitor, navumab na pamuzumab, zikoreshwa mu kuvura kanseri y'umwijima. , ariko ubwoko bwimiterere buroroshye kandi bworoshye kubyara imiti irwanya ibiyobyabwenge.

Mu myaka yashize, itsinda ry’ubushakashatsi rya Chen Jijun ryiyemeje gushakisha imiti igabanya ubukana bwa anti-hepatoma n’imiti igezweho ifite imiterere idasanzwe hamwe n’uburyo bushya bwo gukora buturuka ku bimera bya Artemisia, kandi yashyizeho uburyo bwo gutandukana buhuza icyerekezo cyo kumenya icyerekezo cya sesquiterpene muri Artemisia ibimera hamwe no gukurikirana ibikorwa birwanya hepatoma.Ubu bushakashatsi bwerekanye ku nshuro ya mbere ko ibivuye muri Artemisia annua bifite ibikorwa bikomeye byo guhagarika ingirabuzimafatizo eshatu za hepatoma, kandi ku nshuro ya mbere, ibipimo 36 bya sesquiterpene byerekana ubwoko 9 bwubatswe - Artemisia annua A1-A3, B1-B2, C1-C4 , D, E, F1-F15, G1-G8, H na njye twatandukanijwe nigice gikora cya Artemisia annua.

Ubundi bushakashatsi bwerekanye ko mu bipimo 36 bya sesquiterpene yerekana, ibikorwa bya artemisinin G5 na G7 byari byiza cyane, bikaba byari bihwanye n’umurongo wa mbere w’amavuriro urwanya hepatoma imiti sorafenib;Byongeye kandi, artemisinin yepfo yepfo yerekanaga guhitamo neza numutekano kuruta sorafenib kuri THLE-2 mumyanya myijima isanzwe;Muri icyo gihe, artemisinin G7 yepfo irashobora kandi kubuza ikwirakwizwa rya selile HepG2 muguhagarika gutera no kwimuka kwingirangingo za hepatoma, gutera apoptose no guhagarika ingirabuzimafatizo ya G2 / M.

Ubu bushakashatsi bwerekanye ku nshuro ya mbere urukurikirane rw'ibipimo bya sesquiterpene hamwe na skeleton nshyashya n'imiterere itandukanye muri Artemisia annua, bikungahaza ubwoko bw'imiterere ya sesquiterpene mu bimera bya Artemisia, kandi butanga molekile zitandukanye z'abakandida n'ishingiro rya farumasi kugira ngo hakorwe ubushakashatsi bushya bwo kurwanya anti -ibiyobyabwenge bya hepatoma.

Kugeza ubu, itsinda ry’ubushakashatsi rya Chen Jijun ryatandukanije kandi ryerekana ibipimo 122 bya sesquiterpenoid hamwe n’ibikorwa byo kurwanya hepatoma biva muri Artemisia australis, Artemisia sinica, Artemisia medinalis, Artemisia cowtail na Artemisia mongolica, bingana na 52% by’umubare wa 234 wa sesquiterpenoid. Ibihingwa bya Artemisia kwisi.

Ubuvuzi bwa JinDunifite ubufatanye burambye bwubushakashatsi nubushakashatsi hamwe na tekinoroji yo muri kaminuza zo mu Bushinwa.Hamwe n'ubuvuzi bukomeye bwa Jiangsu, bufitanye umubano w'igihe kirekire n'Ubuhinde, Aziya y'Amajyepfo y'Uburasirazuba, Koreya y'Epfo, Ubuyapani n'andi masoko.Itanga kandi isoko ryisoko nogurisha mubikorwa byose kuva hagati kugeza ibicuruzwa byarangiye API.Koresha ibikoresho byegeranijwe bya Yangshi Chemical muri chimie ya fluor kugirango utange serivisi zidasanzwe zo gutunganya imiti kubafatanyabikorwa.Tanga uburyo bushya bwo gukora no gukora ubushakashatsi bwanduye kubakiriya.

Ubuvuzi bwa JinDun bushimangira gushinga itsinda rifite inzozi, gukora ibicuruzwa byiyubashye, byitondewe, bikomeye, kandi byose bigasohoka kugirango ube umufatanyabikorwa wizewe ninshuti yabakiriya! Umwe mubatanga ibisubizo bihagarika ibisubizo, R&D yihariye hamwe na serivise zitanga umusaruro kubunzi ba farumasi na APIs, abahangaumusaruro wimiti yihariye(CMO) hamwe na farumasi yihariye ya R&D hamwe nabatanga serivisi (CDMO).