• NEBANNER

MOQ yo hasi igurishwa!Uruganda rutanga ibikoresho byiza cyane Betrixaban Ibikoresho bito CAS 330942-05-7

MOQ yo hasi igurishwa!Uruganda rutanga ibikoresho byiza cyane Betrixaban Ibikoresho bito CAS 330942-05-7

Ibisobanuro bigufi:


Ibicuruzwa birambuye

Ibicuruzwa

Kuba intambwe yo gusohoza inzozi z'abakozi bacu!Kubaka itsinda ryishimye, ryunze ubumwe kandi ryiyongera kubanyamwuga!Kugirango tugere kubihembo byabaguzi bacu, abatanga isoko, societe natwe ubwacu kubwa MOQ yo kugurisha bishyushye!Gutanga Uruganda Rwiza Betrixaban Ibikoresho Byibanze CAS 330942-05-7, Turi inyangamugayo kandi turakinguye.Turareba imbere kugirango duhagarare kandi dushyireho umubano wizewe kandi wigihe kirekire.
Kuba intambwe yo gusohoza inzozi z'abakozi bacu!Kubaka itsinda ryishimye, ryunze ubumwe kandi ryiyongera kubanyamwuga!Kugirango tugere kubihembo byabaguzi bacu, abatanga isoko, societe natwe ubwacuUbushinwa Farumasi Hagati na 330942-05-7, "Ubwiza bwiza nigiciro cyiza" ni amahame yubucuruzi.Niba ushishikajwe nigisubizo cyacu cyangwa ufite ikibazo, ibuka kumva utuje.Turizera gushiraho umubano wubufatanye nawe mugihe cya vuba.

Igikorwa cyibinyabuzima cya Fondaparinux

Sobanura Sodium ya Fondaparinux ni antithrombine-iterwa na Xa inhibitor。
Bifitanye isanoIbyiciro inzira yerekana ibimenyetso >> Imisemburo ya metabolike / protease >> Factor Xa Ahantu ubushakashatsi >> Indwara zifata umutima
Intego Ikintu Xa [1]
Muri vitroubushakashatsi Sodium ya Fondaparinux niyo yambere ya anticoagulant ihitamo intego Xa.Kuri Fondaparinux, agaciro ka IC50 (anti-Xa IU / ml) ya monocytes ikora (ac-M) ni 0.59 ± 0.05, naho ibice bikomoka kuri monocyte (MMP) ni 0.17 ± 0.03 [2]。
Muri vivoubushakashatsi Sodium ya Fondaparinux ifite umurongo, ibipimo biterwa na farumasi ya farumasi, itanga igisubizo giteganijwe cyane.Sodium ya Fondaparinux ifite bioavailable 100%, ifite ibikorwa byihuse, ifite igice cyubuzima bwamasaha 14 kugeza 16, kandi irashobora gukomeza kurwanya trombose mumasaha 24.Uyu muti ntabwo uhindura igihe cya prothrombine cyangwa umwanya wa tromboplastine igice, cyangwa ngo ugire ingaruka kumikorere ya platel cyangwa guteranya [1]。
Reba [1].Bauer KA.n'abandi.Sodium ya Fondaparinux: guhitamo inhibitor yibintu Xa.Am J Ubuzima Syst Pharm.2001 Ugushyingo 1; 58 Inyongera 2: S14-7. [2]Ben-Hadj-Khalifa S, n'abandi.Ingaruka zitandukanye za coagulation zibuza fondaparinux, enoxaparin na heparin idacometse muburyo bwimikorere ya selile ya trombine.Amaraso Coagul Fibrinolysis.2011 Nyakanga; 22 (5): 369-73.

Ibikoresho bya chimique na physique ya Fondaparinux

Inzira ya molekulari C31H53N3Na10O49S8
Uburemere bwa molekile 1738.16
PSA 900.82000

Fondaparinux ni ubwoko bushya bw'imiti ya antithrombotique yemejwe na FDA nyuma ya heparin hamwe na heparine ifite uburemere buke bwa heparin yo kuvura no gukumira trombose zitandukanye za arteriovenous.

Ibyerekana: Fondaparinux ikoreshwa kubarwayi barimo kubagwa amagufwa akomeye yo mu maguru yo hepfo, nko kuvunika ikibuno, kubaga ivi rikomeye cyangwa gusimbuza ikibuno, kugirango birinde tromboembolism.Ikoreshwa mukuvura abarwayi bafite angina idahindagurika cyangwa infashanyo ya myocardial itari ST-segiteri yivuza byihutirwa (

1 promotion Glaxo ikomeje guteza imbere isoko izashyira mu mwanya w’ibiyobyabwenge mu nzira ikurikira ivuriro rya Minisiteri y’ubuzima, ivugurura ry’ibiciro rya komisiyo y’igihugu ishinzwe iterambere n’ivugurura, n’ubwishingizi bw’ubuvuzi bwa Minisiteri y’ubwishingizi bw’abaturage.

A 、 Ibicuruzwa bitarinjira mubwishingizi bwubuvuzi bwigihugu.Mu mwaka wa 2010, ubwishingizi bw'ubuvuzi bwinjiye mu bwishingizi bw'ubuvuzi bw'intara 16.Igurisha riri mubyiciro byambere kandi bizagenda bisimbuza buhoro buhoro isoko ya heparin ifite uburemere buke;intara z'ubwishingizi bw'ubuvuzi: Shaanxi, Shanxi, Mongoliya y'imbere, Liaoning, Tibet, Yunnan, Guangdong, Guangxi, Hainan, Jiangsu, Gansu, Fujian, Jiangxi, Henan, Hubei, Beijing.

B 、 Ibimenyetso biracyiyongera.GSK kuri ubu ifite ibimenyetso 3 mu ivuriro.Kurugero, ibyerekana kuri stent byemewe gusa.Izindi heparine ntiziboneka.Gukoresha ivuriro rya stent byiyongera 30% buri mwaka.Hamwe no kwemeza ibimenyetso bishya, kugurisha biziyongera.Mubyigisho, indwara zose zivurwa nibicuruzwa bya heparin zirashobora kuvurwa niki gicuruzwa.

C advantage Inyungu yibiciro, igiciro ntarengwa cyibicuruzwa ku isoko ry’Amerika ni 132 USD buri umwe, mu Bushinwa ni 168 Yuan, igiciro cy’imbere ntikizagabanuka.Niba wohereza hanze, isoko mpuzamahanga rifite umwanya mugari ;

2) Inzira ya tekiniki ni ndende, ibikoresho fatizo bihuzwa mu ntambwe 75, kandi ipatanti yarangiye imyaka 5 (ingingo yo muri 2014).Ntabwo byemewe nabandi bakora.Synthesis iragoye cyane.Ntabwo bizakorwa mugihe kitarenze imyaka 10.Umuzenguruko ni muremure, biragoye, nishoramari.muremure.Hano hari abanywanyi bake murugo, kandi abanyamahanga bahanganye bafite ibiciro byibanze.Intego yacu ni ugukomeza kugabanya ibiciro byibanze no gusimbuza Glaxo mubikorwa fatizo.
Imiti ya Hengrui Fondaparinux yemejwe nkigana bwa mbere mu Bushinwa 2018.
Guangdong Runxing Biotechnology Co., Ltd isohora buri mwaka kg 210 za fondaparinux sodium ya Advanced intermediate N3, izatangwa muri 2018.

Fondaparinux yabanje gukorwa na MYLAN IRELAND.Kugeza ubu, imiti ya Hengrui, imiti ya Borui, Haisco.

Kuba intambwe yo gusohoza inzozi z'abakozi bacu!Kubaka itsinda ryishimye, ryunze ubumwe kandi ryiyongera kubanyamwuga!Kugirango tugere kubihembo byabaguzi bacu, abatanga isoko, societe natwe ubwacu kubwa MOQ yo kugurisha bishyushye!Gutanga Uruganda Rwiza Betrixaban Ibikoresho Byibanze CAS 330942-05-7, Turi inyangamugayo kandi turakinguye.Turareba imbere kugirango duhagarare kandi dushyireho umubano wizewe kandi wigihe kirekire.
MOQ yo hasi yaUbushinwa Farumasi Hagati na 330942-05-7, "Ubwiza bwiza nigiciro cyiza" ni amahame yubucuruzi.Niba ushishikajwe nigisubizo cyacu cyangwa ufite ikibazo, ibuka kumva utuje.Turizera gushiraho umubano wubufatanye nawe mugihe cya vuba.


  • Mbere:
  • Ibikurikira:

  • Andika ubutumwa bwawe hano hanyuma utwohereze