Hydroxypyrazolodpyrimidine pyrazolo (3,4-d) pyrimidin-1-ol
Hydroxypyrazolodpyrimidine pyrazolo (3,4-d) pyrimidin-1-ol
Ikoreshwa mu mavuriro muri Hyperuricemia y'ibanze n'ayisumbuye, cyane cyane ku barwayi barwaye hyperuricemia, ndetse no ku barwayi bafite ikibazo cyo kubura impyiko, no ku barwayi bafite indwara ya goute isubiramo cyangwa idakira, ndetse no ku barwayi barwaye Hyperuricemia.Ikoreshwa mu barwayi barwaye Gouty nephropathie kugirango bagabanye ibimenyetso kandi bagabanye imiterere y'amabuye ya aside irike;amabuye ya gout;ikoreshwa muri uric aside impyiko n'indwara y'impyiko.
Iki gicuruzwa na metabolite yacyo birashobora kubuza okiside ya xanthine, kugirango hypoxanthine na xanthine bidashobora guhinduka aside irike, ni ukuvuga ko synthèse ya acide uric igabanuka, bityo bikagabanya ubukana bwa acide uric mumaraso kandi bikagabanya ubukana bwa urate muri amagufwa, ingingo hamwe nimpyiko, ibiyobyabwenge bishobora kubuza synthesis ya acide uric.Iki gicuruzwa kirashobora guhagarika ibikorwa byimisemburo yimiti yumwijima.
(1).Indwara ya hyperuricemia yibanze niyisumbuye, cyane cyane ifite aside irike ikabije, nayo ikoreshwa kuri hyperuricemia hamwe no kubura impyiko;
(2).Kuvura indwara ya goutte, ikwiranye na goutte isubiramo cyangwa idakira.Ku barwayi barwaye nepropatique, irashobora kugabanya ibimenyetso no kugabanya imiterere y'amabuye ya aside irike mu mpyiko;
(3).Tophi;
(4).Ikoreshwa kuri uric acide impyiko na (cyangwa) acide uric nephropathie.
Bisanzwe ：usp42
Suzuma ：98-102%
Inyuma ：Ifu yera cyangwa hafi yera
Ipaki:25kg / igikapu
Hariho guhagarika amagufwa, bishobora gutera pancytopenia, kandi imiti igomba guhagarikwa nibiba ngombwa.Kunywa amazi menshi mugihe cyo gufata imiti, hanyuma utume inkari zidafite aho zibogamiye cyangwa alkaline kugirango zisohoke aside diureti.Iki gicuruzwa kigomba gukoreshwa nyuma yumuriro ukabije wa gouty arthritis ibuze (mubisanzwe nyuma yibyumweru bibiri nyuma yo gutangira).Mugihe cyo gufata imiti, ishusho yamaraso numwijima nimpyiko bigomba kugenzurwa buri gihe.
JIN DUN Ubuvuzi bufiteImpamyabumenyi ya ISO kandi yujuje ubuziranenge bwa GMP, yakoresheje inzobere mu kuvura ibiyobyabwenge mu gihugu no mu mahanga bifite uburambe bukomeye bwo kuyobora R&D ya sosiyete.
TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
Ubuvuzi bwa Jindun bufite itsinda ryabakozi ba R&D babigize umwuga, kandi bukoresha impuguke nyinshi zo mu gihugu ndetse n’amahanga mu kuvura ibiyobyabwenge kugira ngo ziyobore R&D, bigatuma synthesis yacu neza kandi neza.
Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
1.Hindura abahuza bashya cyangwa APIs.Kimwe nkuko byavuzwe haruguru kugabana, abakiriya bafite ibyo bakeneye kuri Intermediates cyangwa APIs, kandi ntibashobora kubona ibicuruzwa bikenewe kumasoko, noneho turashobora gufasha Customize.
2.Gutunganya neza ibicuruzwa bishaje.Itsinda ryacu rizafasha mugutezimbere no kunoza umusaruro nkuwo inzira ya reaction ishaje, igiciro cyumusaruro ni kinini, kandi imikorere ni mike.Turashobora gutanga ibyangombwa byuzuye byo guhererekanya ikoranabuhanga no kunoza imikorere, gufasha abakiriya kubyara umusaruro mwiza.
Kuva ibiyobyabwenge byibasiye INDs, JIN DUN Medical iraguhaumurongo umwe wihariye R&D ibisubizo.
JIN DUN Ubuvuzi bushimangira gushinga itsinda rifite inzozi, gukora ibicuruzwa byiyubashye, byitondewe, bikomeye, kandi byose kugirango ube umufatanyabikorwa wizewe ninshuti yabakiriya!
![1,4′-Bipiperidine] -1′-karubone ya chloride HCl](http://cdn.globalso.com/jindunchem-med/image211-300x300.png)
