Ibisobanuro bihanitse Gutanga 99% Imidazole / 1h-Imidazole / Imz CAS 288-32-4

Twiyeguriye kugenzura neza no kwita kubaguzi, abakozi bacu b'inararibonye bakorana nabo barashobora kuboneka kugirango baganire kubyo usaba kandi ushimishe abaguzi byuzuye kubisobanuro bihanitse Gutanga 99% Imidazole / 1h-Imidazole / Imz CAS 288-32-4, We ' re witeguye gufatanya ninshuti nziza zumushinga kuva munzu yawe no mumahanga no gukora igihe kirekire cyiza hamwe.
Twiyeguriye kugenzura neza no kwita kubaguzi, abakozi bacu b'inararibonye bakorana nabo barashobora kuboneka kugirango baganire kubyo usaba kandi ushimishe abaguzi byuzuyeUbushinwa Imidazole na Imz, Buri mwaka, benshi mubakiriya bacu basuraga uruganda rwacu kandi bakagera ku iterambere ryinshi mubucuruzi dukorana natwe.Turakwishimiye cyane ko uzadusura igihe icyo aricyo cyose kandi twese hamwe tuzatsinda intsinzi nini mubikorwa byimisatsi.

Hagati ya synthesis ya allopurinol.

Nimwe muma 3-amino-4 yasimbuwe na pyrazole.Irashobora gukoreshwa nkigihe cyo guhuza ibinyabuzima byinshi byifashishwa mu bya farumasi, nka allopurinol, kimwe mu bikomoka kuri pyrazolopyrimidine, icya nyuma kuva mu 1963 Kuva cyakoreshwa mu mavuriro, cyabaye imiti nyamukuru yo kuvura indwara ya goutte.Kugeza ubu, hari uburyo buke buzwi bwo guhuza

3-aminopyrazole-4-carboxamide hemisulfate mu Bushinwa, cyane cyane mugukora malononitrile na triethyl orthoformate kugirango bategure ethoxymethylene malononitrile, hanyuma hamwe na reaction ya hydrazine hydrat itanga 3-amino-4-cyanopyrazole, amaherezo ikabyara aside hamwe na sulfurike yibanze cyane.

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin n'abandi 3-aminopyrazole- Synthesis ya 4-formamide hemisulfate [J]. Inganda zikora imiti, 2008, 6 (22): 39 40), umusaruro wose wa synthesis nubu buryo ni 60% (ubarwa nka malononitrile), ubu buryo burimo intambwe eshatu, reaction ni ndende, na reagent zikoreshwa, nka malononitrile na ethoxymethylene malononitrile, zifite uburozi kandi buhenze.Mubyongeyeho, 3-aminopyrazole-4 yateguwe nubu buryo -Formamide hemisulfate ifite ibara ritoroshye kuyikuramo kandi bisaba gutunganyirizwa hamwe, bigoye cyane.

Hari raporo mubuvanganzo bwamahanga ukoresheje pyridylamide hydrazone na ethoxymethylene malononitrile nkibikoresho fatizo kugirango ubone 3-amino-4-cyanopyrazole wongeyeho na cycleisation, hanyuma ukitwara hamwe na acide sulfurike yibanze kugirango ubone icyerekezo (Reuken G Jones. Ibisubizo bya orthoester hamwe na orthoester hamwe na orthoester hamwe na ifumbire mvaruganda [J]. J Am Chem Soc. 1952.74 (5): 4889 4891).Ibikoresho by'ibanze bikoreshwa muri ubu buryo bihenze, umusaruro wa reaction ntabwo ari mwinshi, kandi inyungu y’umusaruro w’inganda ni muto.Bigomba kuba bigoye.

Ubuyobozi bukuru:Ibipimo ngenderwaho
Inyuma:Ifu yera cyangwa umuhondo

Ipaki:25kg / ingoma
suzuma （HPLC） ibirimo Birarenze cyangwa bingana na 98.0%
ubuziranenge （HPLC） ibirimo Birarenze cyangwa bingana na 99.5%

Twiyeguriye kugenzura neza no kwita kubaguzi, abakozi bacu b'inararibonye bakorana nabo barashobora kuboneka kugirango baganire kubyo usaba kandi ushimishe abaguzi byuzuye kubisobanuro bihanitse Gutanga 99% Imidazole / 1h-Imidazole / Imz CAS 288-32-4, We ' re witeguye gufatanya ninshuti nziza zumushinga kuva munzu yawe no mumahanga no gukora igihe kirekire cyiza hamwe.
Ibisobanuro bihanitseUbushinwa Imidazole na Imz, Buri mwaka, benshi mubakiriya bacu basuraga uruganda rwacu kandi bakagera ku iterambere ryinshi mubucuruzi dukorana natwe.Turakwishimiye cyane ko uzadusura igihe icyo aricyo cyose kandi twese hamwe tuzatsinda intsinzi nini mubikorwa byimisatsi.