Guanosine
Guanosine
Guanosine ikoreshwa nkigihe cya Valaciclovir.
Valacyclovir numuti wa guanine analogue.Ikoreshwa mubuvuzi bwa herpes simplex na herpes zoster kwandura indwara zandurira mu mibonano mpuzabitsina.Ibicuruzwa nibibanziriza acyclovir.Yinjira vuba nyuma yubuyobozi bwo munwa kandi ihinduka vuba acyclovir mumubiri.Ingaruka zayo za virusi ikinwa na acyclovir.Nyuma ya acyclovir yinjiye mu ngirabuzimafatizo zanduye, irushanwa na deoxynucleoside ya virusi thymidine deoxynucleoside kinase cyangwa selile kinase, kandi imiti ikaba fosifori mu buryo bwa acilique guanosine triphosphate.Nka substrate yo kwigana virusi, acyclovir irushanwa na deoxyguanine triphosphate ya virusi ya polymerase ya virusi, ibuza virusi ya ADN kandi ikerekana ingaruka za virusi.Ibikorwa bya virusi yibicuruzwa muri vivo birutwa na acyclovir, kandi igipimo cyo kuvura virusi ya herpes simplex virusi ya I nubwoko bwa II ni 42,91% na 30.13% hejuru ya acyclovir.Ifite kandi ingaruka zikomeye zo kuvura virusi ya varicella zoster.
JIN DUN Ubuvuzi bufiteImpamyabumenyi ya ISO kandi yujuje ubuziranenge bwa GMP, yakoresheje inzobere mu kuvura ibiyobyabwenge mu gihugu no mu mahanga bifite uburambe bukomeye bwo kuyobora R&D ya sosiyete.
TECHNOL OGY INYUNGU
Pressure Umuvuduko mwinshi Catalytic Hydrogenation.Umuvuduko mwinshi Hydrogenolysis reaction.Imyitwarire ya Cryogenic (<-78% C)
● Synthesis ya Aromatic Heterocyclic
Re reaction Kuvugurura
Res Igisubizo cya Chiral
Heck, Suzuki, Negishi, Sonogashira.Gignard
Ibikoresho
Laboratwari yacu ifite ibikoresho bitandukanye byo kugerageza no kugerageza, nka: NMR (Bruker 400M) 、 HPLC 、 chiral-HPLC 、 LC-MS 、 LC-MS / MS (API 4000) 、 IR 、 UV 、 GC 、 GC-MS, Chromatografiya, Microwave Synthesizer, Parallel Synthesizer, Calorimeter itandukanye (DSC), Electron Microscope ...
Itsinda R&D
Ubuvuzi bwa Jindun bufite itsinda ryabakozi ba R&D babigize umwuga, kandi bukoresha impuguke nyinshi zo mu gihugu ndetse n’amahanga mu kuvura ibiyobyabwenge kugira ngo ziyobore R&D, bigatuma synthesis yacu neza kandi neza.
Twafashije amasosiyete menshi yimiti yimiti yo murugo, nkaHansoh, Hengrui na Pharm ya HEC.Hano tuzerekana igice cyabo.
Urubanza rwa Customzation Urubanza rwa mbere:
Cas No.: 110351-94-5
Urubanza rwa Customzation Urubanza rwa kabiri:
Cas No.: 144848-24-8
Urubanza rwa Customzation Urubanza rwa gatatu:
Cas No.: 200636-54-0
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2.Gutunganya neza ibicuruzwa bishaje.Itsinda ryacu rizafasha mugutezimbere no kunoza umusaruro nkuwo inzira ya reaction ishaje, igiciro cyumusaruro ni kinini, kandi imikorere ni mike.Turashobora gutanga ibyangombwa byuzuye byo guhererekanya ikoranabuhanga no kunoza imikorere, gufasha abakiriya kubyara umusaruro mwiza.
Kuva ibiyobyabwenge byibasiye INDs, JIN DUN Medical iraguhaumurongo umwe wihariye R&D ibisubizo.
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