Cyclopropyl 2-fluorobenzyl ketone

Cyclopropyl 2-fluorobenzyl ketone ikoreshwa nkigihe cya Prasugrel.
Prasugrel ni antiplatelet ya thiophenopyridine yakozwe na Eli Lilly na daiichisankyo, uruganda rukora imiti mu Buyapani.Nibiyobyabwenge byabanjirije.Ikora molekile ikora nyuma ya metabolism ikoresheje cytochrome P450 mu mwijima kandi igahuza na reseptor ya P2Y12 kugirango ikore neza kurwanya platine.Ubuvuzi bwa Clinical bwerekanye ko 60 mg ikinini gifite anticoagulant nziza kuruta mg 300 zisanzwe hamwe na 600 mg yiyongereye ya clopidogrel, ishobora kugabanya ibyago byose byindwara z'umutima, ubwonko n'urupfu bitewe n'indwara z'umutima ku kigero cya 20%, kandi bigira ingaruka byihuse , ingaruka nziza zo kuvura, kurwanya ibiyobyabwenge neza na bioavailable, hamwe nuburozi buke.